Multimodal detection of flap endonuclease 1 activity through CRISPR/Cas12a trans-cleavage of single-strand DNA oligonucleotides
Chenyu Cui, Cia‐Hin Lau, Lok Ting Chu, Hoi Kwan Kwong, Chung Tin, Ting‐Hsuan Chen
Topics & Concepts
EndonucleaseDNAOligonucleotideMolecular biologyDNA ligaseChemistryAP siteBiophysicsDuplex (building)Cleavage (geology)BiologyBiochemistryFracture (geology)PaleontologyCRISPR and Genetic EngineeringAdvanced biosensing and bioanalysis techniquesRNA Interference and Gene Delivery