The Protective Mechanism of Dexmedetomidine in Regulating Atg14L-Beclin1-Vps34 Complex Against Myocardial Ischemia-Reperfusion Injury
Yanna Li, Mingcui Qu, Fei Xing, Huixin Li, Dan Cheng, Na Xing, Wei Zhang
Topics & Concepts
AutophagyLY294002PI3K/AKT/mTOR pathwayReperfusion injuryDexmedetomidineProtein kinase BDownregulation and upregulationIschemiaCardiac function curvePharmacologyMedicinePhosphorylationMyocardial ischemiaAnesthesiaChemistryInternal medicineSignal transductionHeart failureBiochemistryApoptosisSedationGeneAutophagy in Disease and TherapyCardiac Ischemia and ReperfusionAdvanced Glycation End Products research