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Fractional Optimal Control Model and Bifurcation Analysis of Human Syncytial Respiratory Virus Transmission Dynamics

Muath Awadalla, Jihan Alahmadi, Kumama Regassa Cheneke, Sania Qureshi

2024Fractal and Fractional33 citationsDOIOpen Access PDF

Abstract

In this paper, the Caputo-based fractional derivative optimal control model is looked at to learn more about how the human respiratory syncytial virus (RSV) spreads. Model solution properties such as boundedness and non-negativity are checked and found to be true. The fundamental reproduction number is calculated by using the next-generation matrix’s spectral radius. The fractional optimal control model includes the control functions of vaccination and treatment to illustrate the impact of these interventions on the dynamics of virus transmission. In addition, the order of the derivative in the fractional optimal control problem indicates that encouraging vaccination and treatment early on can slow the spread of RSV. The overall analysis and the simulated behavior of the fractional optimum control model are in good agreement, and this is due in large part to the use of the MATLAB platform.

Topics & Concepts

Fractional calculusSpectral radiusControl theory (sociology)MATLABOptimal controlTransmission (telecommunications)MathematicsVaccinationBifurcationBasic reproduction numberApplied mathematicsDynamics (music)Control (management)Computer scienceMathematical optimizationVirologyMedicinePhysicsEigenvalues and eigenvectorsPopulationArtificial intelligenceNonlinear systemQuantum mechanicsEnvironmental healthOperating systemTelecommunicationsAcousticsMathematical and Theoretical Epidemiology and Ecology ModelsRespiratory viral infections researchFractional Differential Equations Solutions