Bright red aggregation-induced emission nanoparticles for multifunctional applications in cancer therapy
Liping Zhang, Weilong Che, Zhiyu Yang, Xingman Liu, Shi Liu, Zhigang Xie, Dongxia Zhu, Zhongmin Su, Ben Zhong Tang, Martin R. Bryce
Abstract
NPs can track cells over 14 days, and effectively inhibit tumor growth upon irradiation. To the best of our knowledge, this work is the first example of a PS that integrates image-guided PDT, ultrafast staining and long-term tracing functions, demonstrating the "all-in-one" concept which offers great advantages for potential clinical applications.
Topics & Concepts
Cancer therapyAggregation-induced emissionNanotechnologyNanoparticleCancerCancer treatmentPhotodynamic therapyComputer scienceMaterials scienceChemistryMedicinePhysicsInternal medicineOrganic chemistryQuantum mechanicsFluorescenceLuminescence and Fluorescent MaterialsNanoplatforms for cancer theranosticsAdvanced biosensing and bioanalysis techniques