Structural origin of cooperativity in human hemoglobin: a view from different roles of α and β subunits in the α2β2 tetramer
Shigenori Nagatomo, Masako Nagai, Teizo Kitagawa
Topics & Concepts
TetramerCooperativityChemistryProtein subunitCrystallographyGlobinCooperative bindingMutantProtein quaternary structureStereochemistryHemoglobinBiophysicsBinding siteBiochemistryBiologyGeneEnzymeHemoglobin structure and functionHemoglobinopathies and Related DisordersErythrocyte Function and Pathophysiology