Unreactive C–N Bond Activation of Anilines via Photoinduced Aerobic Borylation
Shuohan Ji, Shengxiang Qin, Chunyu Yin, Lu Luo, Hua Zhang
Abstract
Unreactive C-N bond activation of anilines was achieved by photoinduced aerobic borylation. A diverse range of tertiary and secondary anilines were converted to aryl boronate esters in moderate to good yields with wide functional group tolerance under simple and ambient photochemical conditions. This transformation achieved the direct and facile C-N bond activation of unreactive anilines, providing a convenient and practical route transforming widely available anilines into useful aryl boronate esters.
Topics & Concepts
BorylationChemistryArylFunctional groupPhotochemistryBond cleavageAryl radicalCombinatorial chemistryMedicinal chemistryOrganic chemistryCatalysisAlkylPolymerRadical Photochemical ReactionsCatalytic C–H Functionalization MethodsCatalytic Cross-Coupling Reactions