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Knowledge, Attitudes and Practices Regarding Antibiotic Use and Antibiotic Resistance: A Latent Class Analysis of a Romanian Population

Elena Narcisa Pogurschi, Carmen Daniela Petcu, Alexandru Eugeniu Mizeranschi, Corina‐Aurelia Zugravu, Daniela Cîrnaţu, Ioan Peț, Oana-Mărgărita Ghimpețeanu

2022International Journal of Environmental Research and Public Health29 citationsDOIOpen Access PDF

Abstract

Considering the major limitations of the latest studies conducted in Romania on the knowledge, attitudes and practices (KAPs) of antibiotic use and antibiotic resistance, we conducted this study to assess this major public health threat. A cross-sectional survey based on a validated questionnaire was conducted among the general population of Romania for a period of 5 months, i.e., September 2021–January 2022. The questionnaire was distributed using Google Form and it covered demographic characteristics and KAP assessments consisting of 12 items on knowledge, 10 items on attitudes and 3 items on practices. Latent class analyses (LCAs) were conducted to group respondents based on their responses. The response rate was 77%, of which females responded in a greater number (n = 1251) compared to males (n = 674). For most of the respondents (67.32%, n = 1296), the education level was high school, while 23.58% (n = 454) of respondents were college graduates. One in three Romanians (33.3%) know the WHO predictions related to this topic. Overall, the Romanian population is less disciplined when it comes to completing antibiotic treatments, as 29.19% of the respondents stop the course of antibiotic administration if their symptoms improve. The key findings from the present study may help policy makers in designing targeted interventions to decrease confusion, ambiguity or misconceptions about antibiotic use.

Topics & Concepts

RomanianAntibioticsLatent class modelAntibiotic resistanceClass (philosophy)Resistance (ecology)PopulationMedicineEnvironmental healthMicrobiologyStatisticsBiologyComputer scienceMathematicsArtificial intelligenceEcologyLinguisticsPhilosophyAntibiotic Use and ResistancePharmaceutical Quality and CounterfeitingComplementary and Alternative Medicine Studies