Selective Photoinduced Reduction of Nitroarenes to <i>N</i>-Arylhydroxylamines
Michael G. Kallitsakis, Dimitris I. Ioannou, Michael A. Terzidis, George E. Κostakis, Ioannis N. Lykakis
Abstract
-arylhydroxylamines. The present methodology facilitates this transformation in the absence of catalyst or additives and uses only light and methylhydrazine. This noncatalytic photoinduced transformation proceeds with a broad scope, excellent functional-group tolerance, and high yields. The potential of this protocol reflects on the selective and straightforward conversion of two general antibiotics, azomycin and chloramphenicol, to the bioactive hydroxylamine species.
Topics & Concepts
ChemistryHydroxylamineFunctional groupSelective reductionReduction (mathematics)Transformation (genetics)Combinatorial chemistryMethylhydrazineChloramphenicolCatalysisPhotochemistryAntibioticsOrganic chemistryBiochemistryGeometryPolymerMathematicsGenePropellantNanomaterials for catalytic reactionsAdvanced Photocatalysis TechniquesInnovative Microfluidic and Catalytic Techniques Innovation