Prenylated flavonoid fractions from Glycyrrhiza glabra alleviate insulin resistance in HepG2 cells by regulating the ERK/IRS-1 and PI3K/Akt signaling pathways
De‐Feng Li, Jinling Fan, Lin Du, Guoyan Ren
Topics & Concepts
Insulin receptorGlucose uptakeInsulin resistanceCarbohydrate metabolismGlucose transporterIRS1Protein kinase BGLUT4Snf3GlucokinaseBiochemistryGlycogen synthaseInsulinPI3K/AKT/mTOR pathwayGlycyrrhiza uralensisGlycogenMAPK/ERK pathwaySignal transductionInsulin receptor substrateBiologyEndocrinologyMedicineAlternative medicinePathologyPharmacological Effects of Natural CompoundsGinseng Biological Effects and ApplicationsMedicinal Plants and Bioactive Compounds