Molecular basis of β-arrestin coupling to formoterol-bound β1-adrenoceptor
Yang Lee, Tony Warne, Rony Nehmé, Shubhi Pandey, Hemlata Dwivedi‐Agnihotri, Madhu Chaturvedi, Patricia C. Edwards, Javier García‐Nafría, Andrew G. W. Leslie, Arun K. Shukla, Christopher G. Tate
Topics & Concepts
Heterotrimeric G proteinG protein-coupled receptorG proteinArrestinBeta adrenergic receptor kinaseGq alpha subunitCell biologyTransmembrane domainG protein-coupled receptor kinaseGs alpha subunitBiologyCoupling (piping)ReceptorSignal transductionBiophysicsChemistryBiochemistryMaterials scienceMetallurgyReceptor Mechanisms and SignalingNeuroscience and Neuropharmacology ResearchProtein Kinase Regulation and GTPase Signaling