Discovery of small molecules targeting GRP78 for antiangiogenic and anticancer therapy
Yixue Qiao, Charlotte D’Souza, Abigail Ann Matthews, Yan Jin, Wan He, Jianqiang Bao, Faqin Jiang, Ritu Chandna, Ruowen Ge, Lei Fu
Topics & Concepts
Cancer cellUmbilical veinChemistryCytotoxic T cellCancer researchSmall moleculeCytotoxicityCancerIn vitroPharmacologyCell biologyBiochemistryBiologyMedicineInternal medicineEndoplasmic Reticulum Stress and DiseaseATP Synthase and ATPases ResearchUbiquitin and proteasome pathways