Taurodeoxycholic acid-YAP1 upregulates OTX1 in promoting gallbladder cancer malignancy through IFITM3-dependent AKT activation
Ruifeng Yang, Linhua Yang, Manmei Long, Fengyao Wu, Yongheng Shi, Xia Ran, Junjie Lv, Yiyin Zhang, Yu Lei, Yang Jiao, Chenchen Zhao, Hui Wang, Wei Wei
Topics & Concepts
Cancer researchGallbladder cancerYAP1Protein kinase BDownregulation and upregulationCell growthBiologySignal transductionCancerCell biologyBiochemistryTranscription factorGeneGeneticsHippo pathway signaling and YAP/TAZLipid metabolism and biosynthesisUbiquitin and proteasome pathways