A validated LC-MS/MS method for the quantification of bevacizumab in rat, cynomolgus monkey, and human serum
Ainan Zhou, Jinghua Yu, Yali Wu, Hao Xue, Dafang Zhong, Xingxing Diao
Topics & Concepts
ChemistryChromatographyBevacizumabTandem mass spectrometryMass spectrometryPeptideEnzymatic hydrolysisPharmacokineticsLiquid chromatography–mass spectrometryTrypsinHydrolysisPharmacologyEnzymeBiochemistryChemotherapySurgeryMedicineCancer therapeutics and mechanismsPharmacogenetics and Drug MetabolismCancer Treatment and Pharmacology