Integrating whole-genome sequencing with multi-omic data reveals the impact of structural variants on gene regulation in the human brain
Ricardo A. Vialle, Kátia de Paiva Lopes, David A. Bennett, John F. Crary, Towfique Raj
Topics & Concepts
BiologyExpression quantitative trait lociProgressive supranuclear palsyAlternative splicingGeneticsRNA splicingGeneQuantitative trait locusStructural variationLocus (genetics)HistonePhenotypeGenomeComputational biologySingle-nucleotide polymorphismExonRNAGenotypeAtrophyGenomics and Rare DiseasesGenetic Associations and EpidemiologyGenomic variations and chromosomal abnormalities