Hormones, Hypertrophy, and Hype: An Evidence-Guided Primer on Endogenous Endocrine Influences on Exercise-Induced Muscle Hypertrophy
Derrick W. Van Every, Alysha C. D’Souza, Stuart M. Phillips
Abstract
We review the evidence indicating that endogenous changes in these hormones, including testosterone, growth hormone, insulin growth factor-1, and estrogen, and their proposed anabolic effects contribute to and augment resistance exercise training (RET)-induced hypertrophy. Additionally, we provide recommendations for gold-standard methodological rigor to establish best practices for verifying menstrual phases as part of their research, ultimately enhancing our understanding of the impact of ovarian hormones on RET-induced adaptations.
Topics & Concepts
Muscle hypertrophyEndogenyHormoneEndocrinologyEndocrine systemInternal medicineMedicineMuscle metabolism and nutritionExercise and Physiological ResponsesSports Performance and Training