FOXM1-activated IGF2BP3 promotes cell malignant phenotypes and M2 macrophage polarization in hepatocellular carcinoma by inhibiting ferroptosis via stabilizing RRM2 mRNA in an m6A-dependent manner
Heng Gao, Lei Shi, Jinfeng Liu, Yingren Zhao, Fenjing Du, Yingli He, Xin Yang, Ning Song, Juan Wen, Gezhi Zheng
Topics & Concepts
Gene knockdownCancer researchChemistryCell growthCarcinogenesisCell biologyBiologyApoptosisGeneBiochemistryFerroptosis and cancer prognosisRNA modifications and cancerImmune cells in cancer