Pancreatic lipase inhibitory activity of <i>Bambusa multiplex</i> cv. <i>Fernleaf</i> leaf extract <i>in vitro</i> and <i>in vivo</i>
Ying Li, Bo Chen, Hai‐Yan Cao, Jingen Li, Lingli Chen, Qing‐Feng Zhang
Abstract
, respectively. The extract could bind to pancreatic lipase and showed mixed-type inhibition. An in vivo study showed that pre-administration of B. multiplex extract significantly reduced the fat absorption in rats and increased fat excretion through feces. The change in the C-glycosyl flavonoid content in feces was the same as that in the triglyceride content. The inhibitory activity of B. multiplex leaf extract on pancreatic lipase was confirmed both in vitro and in vivo.
Topics & Concepts
In vivoChemistryVitexinLipaseIsoorientinIC50BiochemistryIn vitroFlavonoidChromatographyBiologyEnzymeBiotechnologyAntioxidantBamboo properties and applicationsPharmacology and Obesity TreatmentBioactive natural compounds