The challenge of ventilator-associated pneumonia diagnosis in COVID-19 patients
Bruno François, Pierre-François Laterre, Charles‐Édouard Luyt, Jean Chastre
Abstract
While different phenotypes have been evidenced in ICU COVID-19 pneumonia [1], most patients meet ARDS Berlin definition associating bilateral radiologic infiltrates with severe hypoxemia. COVID-19 patients frequently require prolonged invasive mechanical ventilation (MV) including prone positioning, heavy sedation, and muscle blockers for several weeks. In addition, there is clear evidence of prolonged immunosuppression including deep lymphopenia [...]
Topics & Concepts
Coronavirus disease 2019 (COVID-19)Pneumonia2019-20 coronavirus outbreakSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)MedicineVentilator-associated pneumoniaIntensive care medicineVirologyInternal medicineOutbreakInfectious disease (medical specialty)DiseaseNosocomial Infections in ICUPneumonia and Respiratory InfectionsAntibiotic Use and Resistance