Synthesis of 1,3,4-oxadiazole derivatives with anticonvulsant activity and their binding to the GABAA receptor
Shiben Wang, Hui Liu, Xuekun Wang, Kang Lei, Guangyong Li, Jun Li, Renmin Liu, Zhe‐Shan Quan
Topics & Concepts
GABAA receptorChemistryAnticonvulsantEthosuximideED50NeurotoxicityPharmacologyIn vivoAnxiolyticCarbamazepineStereochemistryBenzodiazepinePharmacokineticsLead compoundDocking (animal)ReceptorIn vitroToxicityBiochemistryEpilepsyOrganic chemistryMedicineNursingPsychiatryBiotechnologyBiologyCholinesterase and Neurodegenerative DiseasesNeuroscience and Neuropharmacology ResearchElectrochemical Analysis and Applications