Lipopolysaccharide-Induced Exosomal miR-146a Is Involved in Altered Expression of Alzheimer’s Risk Genes Via Suppression of TLR4 Signaling
Junling Yang, Fiona Malone, Michelle Sy Go, Jinghong Kou, Jeong-Eun Lim, R.C. Caughey, Ken-ichiro Fukuchi
Topics & Concepts
MicrogliaTLR4LipopolysaccharideInflammationDownregulation and upregulationImmunologyToll-like receptorReceptorTumor necrosis factor alphaNeuroinflammationBiologyCell biologyInnate immune systemMedicineInternal medicineImmune systemGeneBiochemistryNeuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatmentsS100 Proteins and Annexins