Targeting Xkr8 via nanoparticle-mediated in situ co-delivery of siRNA and chemotherapy drugs for cancer immunochemotherapy
Yuang Chen, Yixian Huang, Qinzhe Li, Zhangyi Luo, Ziqian Zhang, Haozhe Huang, Jingjing Sun, LinXinTian Zhang, Runzi Sun, Daniel J. Bain, James F. Conway, Binfeng Lu, Song Li
Topics & Concepts
NanocarriersCancer researchProdrugIn vivoImmune systemCancer cellImmunogenic cell deathCancerImmunosuppressionApoptosisSmall interfering RNADownregulation and upregulationChemotherapyPharmacologyChemistryBiologyImmunotherapyDrugImmunologyTransfectionCell cultureBiochemistryGeneBiotechnologyGeneticsPhagocytosis and Immune RegulationRNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery