DAMPs/PAMPs induce monocytic TLR activation and tolerance in COVID-19 patients; nucleic acid binding scavengers can counteract such TLR agonists
Ibtehaj A. Naqvi, Nicholas Giroux, Lyra B. Olson, Sarah A. Morrison, Telmo Llanga, Tolulope Akinade, Yuefei Zhu, Yiling Zhong, Shree Bose, Stephanie Arvai, Karen Abramson, Lingye Chen, Loretta G. Que, Bryan Kraft, Xiling Shen, Jae Wook Lee, Kam W. Leong, Smita K. Nair, Bruce A. Sullenger
Topics & Concepts
Nucleic acidInnate immune systemCell biologyCoronavirus disease 2019 (COVID-19)PhagocytosisMaterials scienceImmunologyBiologyImmune systemBiochemistryMedicineDiseaseInfectious disease (medical specialty)PathologyCOVID-19 Clinical Research StudiesRespiratory Support and MechanismsPneumonia and Respiratory Infections