CDK5 inhibition protects against OGDR induced mitochondrial fragmentation and apoptosis through regulation of Drp1S616 phosphorylation
Chunli Chen, Xiaoxia Peng, Jiayu Tang, Zhiping Hu, Jieqiong Tan, Liuwang Zeng
Topics & Concepts
Cyclin-dependent kinase 5PhosphorylationApoptosisNeuroprotectionCell biologyTransfectionBiologyMolecular biologyKinaseChemistryProtein kinase ACell cultureCyclin-dependent kinase 2BiochemistryPharmacologyGeneticsMitochondrial Function and PathologyMicrotubule and mitosis dynamicsAutophagy in Disease and Therapy