Optical and Fluorescent Dual Sensing of Aminoalcohols by in Situ Generation of BODIPY-like Chromophore
Mukesh E. Shirbhate, Seongyeon Kwon, Ayoung Song, Seungha Kim, Dayeh Kim, Haofei Huang, Youngmee Kim, Hanna Lee, Sung‐Jin Kim, Mu‐Hyun Baik, Juyoung Yoon, Kwan Mook Kim
Abstract
A novel multifunctional aminophenylboronic acid connected to a diphenylketone gives both circular dichroism and fluorescence signals by in situ generation of a BODIPY-like chromophore in the presence of aminoalcohols. DFT calculations were used to understand the role of each functional group in the mechanism. This new sensor can distinguish different aminoalcohols and quantitatively indicate the concentration of the substrate, allowing for the convenient determination of the ee of racemic mixtures with a single probe.
Topics & Concepts
ChemistryChromophoreBODIPYFluorescenceIn situPhotochemistryCircular dichroismSubstrate (aquarium)StereochemistryOrganic chemistryOpticsGeologyPhysicsOceanographyLuminescence and Fluorescent MaterialsMolecular Sensors and Ion DetectionPorphyrin and Phthalocyanine Chemistry