Coronary Artery Ectasia: Review of the Non-Atherosclerotic Molecular and Pathophysiologic Concepts
Gavin H. C. Richards, Kathryn L. Hong, Michael Y. Henein, Colm G. Hanratty, Usama Boles
Abstract
Coronary artery ectasia (CAE) is frequently encountered in clinical practice, conjointly with atherosclerotic CAD (CAD). Given the overlapping cardiovascular risk factors for patients with concomitant CAE and atherosclerotic CAD, a common underlying pathophysiology is often postulated. However, coronary artery ectasia may arise independently, as isolated (pure) CAE, thereby raising suspicions of an alternative mechanism. Herein, we review the existing evidence for the pathophysiology of CAE in order to help direct management strategies towards enhanced detection and treatment.
Topics & Concepts
Coronary artery ectasiaPathophysiologyMedicineEctasiaCardiologyInternal medicineCoronary artery diseaseArteryCADConcomitantCoronary angiographyMyocardial infarctionBiologyBiochemistryKawasaki Disease and Coronary ComplicationsCoronary Artery AnomaliesBlood Coagulation and Thrombosis Mechanisms