Porous Structural Microfluidic Device for Biomedical Diagnosis: A Review
Luyao Chen, Xin Guo, Xidi Sun, Shuming Zhang, Jing Wu, Huiwen Yu, Tongju Zhang, Wen Cheng, Yi Shi, Lijia Pan
Abstract
Microfluidics has recently received more and more attention in applications such as biomedical, chemical and medicine. With the development of microelectronics technology as well as material science in recent years, microfluidic devices have made great progress. Porous structures as a discontinuous medium in which the special flow phenomena of fluids lead to their potential and special applications in microfluidics offer a unique way to develop completely new microfluidic chips. In this article, we firstly introduce the fabrication methods for porous structures of different materials. Then, the physical effects of microfluid flow in porous media and their related physical models are discussed. Finally, the state-of-the-art porous microfluidic chips and their applications in biomedicine are summarized, and we present the current problems and future directions in this field.