Hydrophobic immiscibility controls self-sorting or co-assembly of peptide amphiphiles
Rie Wakabayashi, Rino Imatani, Mutsuhiro Katsuya, Yuji Higuchi, Hiroshi Noguchi, Noriho Kamiya, Masahiro Goto
Abstract
Pairs of peptide amphiphiles with immiscible hydrophobic tails were synthesized and their assembly formation was investigated. These pairs formed self-sorting supramolecular fibres using a standard heating-cooling protocol, while one pair with longer hydrophobic tails formed a co-assembly when an additional heating process was applied.
Topics & Concepts
AmphiphileSupramolecular chemistrySelf-assemblyPeptideSortingChemistryHydrophobic effectChemical engineeringMaterials scienceOrganic chemistryCopolymerMoleculeBiochemistryPolymerComputer scienceEngineeringProgramming languageSupramolecular Self-Assembly in MaterialsPolydiacetylene-based materials and applicationsChemical Synthesis and Analysis