pH-Responsive Metal–Organic Framework Thin Film for Drug Delivery
Steven G. Guillen, Jacob Parres-Gold, Angel Ruiz, Ethan Lucsik, Benjamin Dao, Tran K. L. Hang, Megan Chang, Adaly Garcia, Yixian Wang, Fangyuan Tian
Abstract
and the carboxylate ligands is the leading cause of drug release in acidic conditions. This work exhibits the potential of using MOF thin films as pH-triggered drug delivery systems.
Topics & Concepts
Quartz crystal microbalanceIbuprofenDrug deliveryChemistryCarboxylateDissociation (chemistry)Thin filmChemical engineeringCalcinationSurface plasmon resonanceInorganic chemistryNanotechnologyMaterials scienceStereochemistryOrganic chemistryAdsorptionNanoparticleCatalysisPharmacologyEngineeringMedicineMetal-Organic Frameworks: Synthesis and ApplicationsNanoplatforms for cancer theranosticsCrystallography and molecular interactions