Enhanced Efficacy of Chemotherapy by Addition of Immune Checkpoint Inhibitors in Stage IV Large Cell Neuroendocrine Carcinoma of the Lung: A Real-World Analysis
Lingbin Meng, Biwei Cao, Rui Ji, Dung‐Tsa Chen, Damian A. Laber, Michael Shafique
Abstract
Our results suggest that the combination of immunotherapy with chemotherapy holds potential for improving outcomes in stage IV LCNEC. Despite the retrospective nature and limited sample size of our study, these preliminary findings provide a valuable insight into the potential of immunotherapy in LCNEC treatment and encourage further research through larger, prospective trials.
Topics & Concepts
MedicineInternal medicineLung cancerStage (stratigraphy)MalignancyUnivariate analysisOncologyHazard ratioChemotherapyProportional hazards modelGastroenterologyImmunotherapyProgression-free survivalCancerMultivariate analysisConfidence intervalPaleontologyBiologyNeuroendocrine Tumor Research AdvancesLung Cancer Research StudiesLung Cancer Treatments and Mutations