Transition‐metal free synthesis of <scp>2‐pyrones</scp> by [3 + 3] annulation of cyclopropenones and sulfur ylides
Cheng Yuan, Qingqing Wang, Tao Feng, Ji‐Kai Liu, William Cheung, Gangqiang Wang, Shaofa Sun, Yalan Xing
Abstract
Abstract A simple and efficient synthesis for 2‐pyrones by [3 + 3] annulation of cyclopropenones and sulfur ylides in the presence of triethyl amine as a base has been developed featuring transition‐metal free conditions, high yields, and excellent functional group compatibility. Using this process, a variety of 2‐pyrones were prepared in good to excellent yields.
Topics & Concepts
ChemistryAnnulationSulfurAmine gas treatingTransition metalCombinatorial chemistryOrganic chemistryCatalysisCyclopropane Reaction MechanismsCatalytic C–H Functionalization MethodsCatalytic Alkyne Reactions