COVID-19-Associated Cytotoxic Lesions of the Corpus Callosum
Pritika Gaur, Luke Dixon, B. Jones, Hermione Lyall, Wajanat Jan
Abstract
There are very limited published data on the neurologic complications associated with coronavirus disease 2019 (COVID-19) in the pediatric population. Here we present the first 2 pediatric cases of presumed COVID-19 related cytotoxic lesions of the corpus callosum. Similar to reports in adults, these cases suggest that the COVID-19 infection in children may rarely mediate a hyperinflammatory response that can cause CNS pathology. As the pandemic continues further, the presentation of cytotoxic lesions of the corpus callosum should prompt radiologists to consider COVID-19, among other known causes.
Topics & Concepts
Corpus callosumMedicineCoronavirus disease 2019 (COVID-19)Cytotoxic T cellPandemicPathologyPresentation (obstetrics)PopulationDiseaseInfectious disease (medical specialty)SurgeryBiologyEnvironmental healthBiochemistryIn vitroInfectious Encephalopathies and EncephalitisLong-Term Effects of COVID-19Infectious Diseases and Tuberculosis