Deciphering mechanistic and therapeutic insight of pyrazolopyrimidines into MRSA suppression: comprehensive in vitro and in vivo study
Vishwani Jamwal, Tashi Palmo, Diksha Kumari, Samriti Dogra, Somdutt Mujwar, Ramajayan Pandian, Kuljit Singh
Topics & Concepts
In vivoIn silicoDNA gyraseChemistryIn vitroComputational biologyPharmacologyDrug discoveryAntibacterial activityStaphylococcus aureusIn vitro toxicologyAntimicrobialBiocompatible materialAntibacterial agentDocking (animal)BiofilmDrug developmentStructure–activity relationshipCancer therapeutics and mechanismsAntimicrobial Peptides and ActivitiesPhenothiazines and Benzothiazines Synthesis and Activities