Litcius/Paper detail

Spatial genomics enables multi-modal study of clonal heterogeneity in tissues

Tongtong Zhao, Zachary Chiang, Julia W. Morriss, Lindsay M. LaFave, Evan Murray, Isabella Del Priore, Kevin Meli, Caleb A. Lareau, Naeem Nadaf, Jilong Li, Andrew Earl, Evan Z. Macosko, Tyler Jacks, Jason D. Buenrostro, Fei Chen

2021Nature272 citationsDOIOpen Access PDF

Topics & Concepts

BiologyComputational biologyGenomicsTumour heterogeneityGeneDNA sequencingTranscriptomeGenomePhenotypeGenetic heterogeneityGeneticsCancerGene expressionSingle-cell and spatial transcriptomicsCancer Genomics and DiagnosticsCRISPR and Genetic Engineering