Development of [<sup>18</sup>F]AldoView as the First Highly Selective Aldosterone Synthase PET Tracer for Imaging of Primary Hyperaldosteronism
Kerstin Sander, Thibault Gendron, Klaudia Cybulska, Fatih Sirindil, Junhua Zhou, Tammy L. Kalber, Mark F. Lythgoe, Tom Kurzawinski, Morris J. Brown, Bryan Williams, Erik Årstad
Abstract
F]AldoView is a promising tracer for the detection of APAs in patients with PHA.
Topics & Concepts
HyperaldosteronismChemistryAldosteroneAldosterone synthaseTRACERPositron emission tomographyAdrenal cortexRadiochemistryEndocrinologyNuclear medicineBiochemistryMedicineBlood pressureRenin–angiotensin systemNuclear physicsPhysicsHormonal Regulation and HypertensionAdrenal and Paraganglionic TumorsPharmacogenetics and Drug Metabolism