An RNA-based catalytic hairpin assembly circuit coupled with CRISPR-Cas12a for one-step detection of microRNAs
Pinru Chen, Luying Wang, Peipei Qin, Bin‐Cheng Yin, Bang‐Ce Ye
Topics & Concepts
Trans-activating crRNACRISPRNucleaseRNARNase PNucleic acidLoop-mediated isothermal amplificationmicroRNAComputational biologyChemistryGuide RNADetection limitNanotechnologyCas9BiologyDNABiochemistryMaterials scienceGeneChromatographyAdvanced biosensing and bioanalysis techniquesCRISPR and Genetic EngineeringRNA Interference and Gene Delivery