An elastase nanocomplex with metal cofactors for enhancement of target protein cleavage activity and synergistic antitumor effect
Chuanda Zhu, Xi Chen, Jingjing Gong, Jiao Liu, Lidong Gong, Zeliang Yang, Zhenyu Zhu, Qiang Zhang, Tiancheng Li, Ling Liang, Zhiqiang Lin
Topics & Concepts
ChemistryElastaseIn vivoIn vitroCleavage (geology)Serine proteaseProteasesNeutrophil elastaseTransmembrane proteinCancer researchImmune systemCell biologyBiochemistryProteasePharmacologyEnzymeInflammationImmunologyBiologyReceptorPaleontologyFracture (geology)BiotechnologyProtease and Inhibitor MechanismsNanoplatforms for cancer theranosticsPeptidase Inhibition and Analysis