Federated Learning in Smart Healthcare: A Survey of Applications, Challenges, and Future Directions
Mohammad Nasajpour, Seyedamin Pouriyeh, Reza M. Parizi, Meng Han, Fatemeh Mosaiyebzadeh, Liyuan Liu, Yixin Xie, Daniel Macêdo Batista
Abstract
In recent years, novel technologies in smart healthcare systems have opened significant opportunities for diagnosis and treatment across various medical fields. Federated Learning (FL), a decentralized machine learning approach, trains shared models using local data from devices like wearables and hospital systems without transferring sensitive information, offering a promising solution to privacy challenges in areas such as cancer prediction, COVID-19 detection, drug discovery, and medical image processing. This literature survey reviews FL architectures (e.g., FedHealth, PerFit), applications, and recent advancements, demonstrating their impact on healthcare through enhanced predictive models for patient care. Key findings include improved accuracy in wearable-based diagnostics and secure multi-institutional collaboration, though limitations persist. We also highlight open challenges, such as security risks, communication costs, and data heterogeneity, which require further research attention.