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Synthesis and in vitro anticancer activity of 4H-pyrano[2,3-d]pyrimidine−1H-1,2,3-triazole hybrid compounds bearing D-glucose moiety with dual EGFR/HER2 inhibitory activity and induced fit docking study

Nguyễn Đình Thành, Do Son Hai, Le Thi Huyen, Nguyễn Thị Kim Giang, Nguyễn Thị Thu Hà, Do Tien Tung, Cao Thi Le, Hoàng Thi Kim Van, Vũ Ngọc Toán

2022Journal of Molecular Structure29 citationsDOI

Topics & Concepts

ChemistryPropargylDocking (animal)HeLaClick chemistryPyrimidine1,2,3-TriazoleTriazoleMoietyStereochemistryCatalysisCombinatorial chemistryIn vitroOrganic chemistryBiochemistryMedicineNursingClick Chemistry and ApplicationsSynthesis and Characterization of Heterocyclic CompoundsSynthesis and biological activity
Synthesis and in vitro anticancer activity of 4H-pyrano[2,3-d]pyrimidine−1H-1,2,3-triazole hybrid compounds bearing D-glucose moiety with dual EGFR/HER2 inhibitory activity and induced fit docking study | Litcius