Structure-Based Design of α-Substituted Mercaptoacetamides as Inhibitors of the Virulence Factor LasB from <i>Pseudomonas aeruginosa</i>
Cansu Kaya, Isabell Walter, Alaa Alhayek, Roya Shafiei, Gwenaëlle Jézéquel, Anastasia Andreas, Jelena Konstantinović, Esther Schönauer, Asfandyar Sikandar, Jörg Haupenthal, Rolf Müller, Hans Brandstetter, Rolf W. Hartmann, Anna K. H. Hirsch
Abstract
culture supernatant.
Topics & Concepts
Pseudomonas aeruginosaMicrobiologyVirulenceGalleria mellonellaBacteriaVirulence factorBiologyElastaseImmune systemPathogenic bacteriaImmunologyEnzymeBiochemistryGeneGeneticsAntimicrobial Peptides and ActivitiesBacterial biofilms and quorum sensingAntibiotic Resistance in Bacteria