Protective effect of Saxagliptin on diabetic rats with renal ischemia reperfusion injury by targeting oxidative stress and mitochondrial apoptosis pathway through activating Nrf-2/HO-1 signaling
Yu Tang, Yan-fei Leng, Wei Wang, Jiong Zhang, Tong-ling Yuan, Jia Wang
Topics & Concepts
Oxidative stressPharmacologyApoptosisCytochrome cTUNEL assaySOD2ChemistryReperfusion injuryMedicineEndocrinologyInternal medicineSuperoxide dismutaseBiochemistryIschemiaAdenosine and Purinergic SignalingAdvanced Glycation End Products researchHeme Oxygenase-1 and Carbon Monoxide