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Recent Applications of Pillar[<i>n</i>]arene-Based Host–Guest Recognition in Chemosensing and Imaging

Yutong Li, Jia Wen, Jiangshan Li, Zejia Wu, Wei Li, Kui Yang

2021ACS Sensors62 citationsDOI

Abstract

Pillar[n]arene is a novel kind of synthetic supramolecular macrocyclic host characterized by its particular pillar-shaped structure consisting of an electron-rich cavity and two finely adjustable rims. Benefiting from its rigid structure, facile synthesis, ease of functionalization, and outstanding host–guest chemistry, pillar[n]arene shows great potential for diverse applications. Significantly, the host–guest recognition of pillar[n]arene provides a novel approach for chemosensing and imaging. Herein, this Review critically and comprehensively reviews the applications of pillar[n]arene-based host–guest recognition in chemosensing and imaging. The sensing and imaging mechanisms as well as the unique roles and advantages of pillar[n]arene-based host–guest recognition are summarized. In addition, preparations of hybrid materials based on pillar[n]arene and inorganic materials are also introduced comprehensively in the light of chemosensing and imaging. Finally, current challenges and perspectives on pillar[n]arene-based host–guest recognition in chemosensing and imaging are outlined.

Topics & Concepts

PillarMolecular recognitionHost (biology)NanotechnologyMaterials scienceChemistryMoleculeEngineeringOrganic chemistryBiologyStructural engineeringEcologyMolecular Sensors and Ion DetectionSupramolecular Chemistry and ComplexesSupramolecular Self-Assembly in Materials
Recent Applications of Pillar[<i>n</i>]arene-Based Host–Guest Recognition in Chemosensing and Imaging | Litcius