Litcius/Paper detail

Pegloticase co-administered with high MW polyethylene glycol effectively reduces PEG-immunogenicity and restores prolonged circulation in mouse

Zhongbo Li, Limei Shen, Alice Ma, Anne Talkington, Zibo Li, Andrew C. Nyborg, M. Scott Bowers, Brian LaMoreaux, Eric W. Livingston, Jonathan E. Frank, Hong Yuan, Samuel K. Lai

2023Acta Biomaterialia16 citationsDOIOpen Access PDF

Topics & Concepts

ImmunogenicityPEG ratioPolyethylene glycolPharmacologyAntibodyImmune systemMedicinePEGylationChemistryImmunologyBiochemistryFinanceEconomicsRNA Interference and Gene DeliveryMonoclonal and Polyclonal Antibodies ResearchNanoparticle-Based Drug Delivery