Estimating changes in antibiotic consumption in the USA with the introduction of doxycycline post-exposure prophylaxis
Kirstin Roster, Yonatan H. Grad
Abstract
Doxycycline as a post-exposure prophylaxis (doxy-PEP) reduced the risk of bacterial sexually transmitted infections (STIs) in a randomised controlled trial of men who have sex with men taking HIV pre-exposure prophylaxis (PrEP), transgender women taking HIV PrEP, and people living with HIV.1 There is concern that increased consumption of doxycycline might increase antimicrobial resistance, including doxycycline-resistant Neisseria gonorrhoeae, Staphylococcus aureus, and Streptococcus pneumoniae.
Topics & Concepts
DoxycyclineMedicineStreptococcus pneumoniaePre-exposure prophylaxisAntimicrobialNeisseria gonorrhoeaeHuman immunodeficiency virus (HIV)Men who have sex with menAntibioticsAntibiotic resistanceStaphylococcus aureusSyphilisMicrobiologyImmunologyBiologyBacteriaGeneticsReproductive tract infections researchHIV, Drug Use, Sexual RiskSyphilis Diagnosis and Treatment