NSUN2-mediated RNA m<sup>5</sup>C modification modulates uveal melanoma cell proliferation and migration
Guangying Luo, Weiwei Xu, Xiaoyan Chen, Siqi Wang, Jiao Wang, Feng Dong, Dan‐Ning Hu, Peter S. Reinach, Dongsheng Yan
Abstract
C methylation provides a potential novel target to improve the therapeutic management of UM pathogenesis.
Topics & Concepts
BiologyRNAMethylationMolecular biologyCell growthGene knockdownSmall interfering RNACellCell biologyDownregulation and upregulationCancer researchCell cultureGeneticsGeneCancer-related molecular mechanisms researchRNA modifications and cancerinterferon and immune responses