Enantioselective Total Synthesis of (+)-Heilonine
Kyle Cassaidy, Viresh H. Rawal
Abstract
), achieved in 21 steps starting from ethyl vinyl ketone.
Topics & Concepts
CycloisomerizationChemistryEnantioselective synthesisIntramolecular forceTotal synthesisStereochemistryRing (chemistry)PropargylKetoneCombinatorial chemistryCatalysisOrganic chemistryPhytochemical compounds biological activitiesBiochemical and Structural CharacterizationBerberine and alkaloids research