Selenium-engineered covalent organic frameworks for high-efficiency and long-acting cancer therapy
Xiuyan Wan, Tong Wu, Liqun Song, Wei Pan, Na Li, Bo Tang
Abstract
A porphyrin-containing covalent organic framework (COF) was synthesized as a substrate for decorating selenium nanoparticles (Se NPs) via in situ reduction. Se NP-mediated therapy (SeT) was carried out in conjunction with photodynamic therapy (PDT) to provide an increased anticancer effect and remedy the constrained efficacy of PDT.
Topics & Concepts
SeleniumCovalent bondCancer therapyChemistryNanotechnologyCancerCombinatorial chemistryMaterials scienceOrganic chemistryMedicineInternal medicineNanoplatforms for cancer theranosticsCarbon and Quantum Dots ApplicationsCovalent Organic Framework Applications