Inhibition of 5-lipoxygenase is associated with downregulation of the leukotriene B4 receptor 1/ Interleukin-12p35 pathway and ameliorates sepsis-induced myocardial injury
Saiyang Xie, Xiping Qi, Qingqing Wu, Wei Li, Min Zhang, Xing Yun, Wenke Shi, Si Chen, Xiaofeng Zeng, Shasha Wang, Haipeng Guo, Wei Deng
Topics & Concepts
SepsisMedicineLeukotriene B4PharmacologyInflammationArachidonate 5-lipoxygenaseDownregulation and upregulationImmunologyBiologyArachidonic acidBiochemistryGeneEnzymeImmune Response and InflammationImmune cells in cancerSepsis Diagnosis and Treatment