4-Hydroxy-2-pyridone derivatives with antitumor activity produced by mangrove endophytic fungus Talaromyces sp. CY-3
Wencong Yang, Bingzhi Zhang, Qi Tan, Yan Chen, Tao Chen, Ge Zou, Bing Sun, Bo Wang, Jie Yuan, Zhigang She
Topics & Concepts
ChemistryCell cycle checkpointCell cycleCytotoxicityCell growthIn vitroFlow cytometryCell cultureWestern blotStereochemistryA549 cellGrowth inhibitionIC50BiochemistryCellMolecular biologyBiologyGeneGeneticsMicrobial Natural Products and BiosynthesisPeptidase Inhibition and AnalysisUbiquitin and proteasome pathways