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Exploration of components and mechanisms of Polygoni Multiflori Radix-induced hepatotoxicity using siRNA -mediated CYP3A4 or UGT1A1 knockdown liver cells

HU Yinghuan, Dengke Li, Zhengyang Quan, Chengyu Wang, Ming Zhou, Zhenxiao Sun

2021Journal of Ethnopharmacology22 citationsDOI

Topics & Concepts

EmodinGene knockdownRadix (gastropod)ApoptosisViability assayPharmacologyChemistryLiver injuryFlow cytometryHigh-performance liquid chromatographyTraditional medicineBiologyBiochemistryChromatographyMolecular biologyMedicineBotanyPhytochemistry and biological activity of medicinal plantsDrug-Induced Hepatotoxicity and ProtectionMangiferin and Mango Extracts
Exploration of components and mechanisms of Polygoni Multiflori Radix-induced hepatotoxicity using siRNA -mediated CYP3A4 or UGT1A1 knockdown liver cells | Litcius