Deubiquitinating enzyme OTUD4 stabilizes RBM47 to induce ATF3 transcription: a novel mechanism underlying the restrained malignant properties of ccRCC cells
Ziyao Li, Ye Tian, Huafeng Zong, Xuelei Wang, Dongyang Li, Adili Keranmu, Shiyong Xin, Bowen Ye, Rong Bai, Weihua Chen, Guosheng Yang, Ye Lin, Siyan Wang
Topics & Concepts
Clear cell renal cell carcinomaCancer researchDeubiquitinating enzymeDownregulation and upregulationTranscription factorBiologyCell growthATF3Tumor progressionCancerUbiquitinGene expressionMedicinePathologyRenal cell carcinomaGenePromoterBiochemistryGeneticsRNA modifications and cancerCancer-related gene regulationFerroptosis and cancer prognosis